Biospecimen Collection
Collection of various human biospecimen carried out by well-trained research staff.
Biospecimen Processing
The facility is equipped with all the required equipment and trained manpower for sample processing
Biospecimen Archival
Highly sophisticated and well-planned archival facility with a capacity of storing >1.6 million biospecimen
Biospecimen Retrieval
Well-governed retrieval process with strict adherence to protocols for sharing the biospecimen
About Us
The biorepository facility at the NCR Biotech Science Cluster is one of the largest and most varied research bioresource centre in India. The facility was established in 2015 to provide support to the DBT funded pregnancy cohort study - ”Interdisciplinary Group of Advanced Research Birth Outcomes, a DBT India Initiative (GARBH-INI)” at THSTI. In 2019, it was identified as a separate platform in the Translational Research Program (TRP) with a mandate to expand to other programs in the NCR Biotech Science Cluster and beyond. It hosts a wide array of biospecimen with detailed clinical and demographic information.
In 2020, the biorepository facility at the NCR Biotech Science Cluster was notified as one in the network biorepositories of National COVID-19 bioresource of well-phenotyped clinical samples by ICMR, Govt. of India.
Currently, biorepository facility archives > 1.2 million varied biospecimen from health/disease-based longitudinal cohorts for biomarker development/ validation and for seroprevalence studies (blood, serum, plasma, urine, saliva, placental tissue, NP/OP swabs, DNA & PBMCs etc.). The team facilitates the requesters on the study design based on sample availability and study objectives. All participant IDs are de-identified by the use of Unique Identification Code (UIC) and the archived biospecimen are also tagged with alphanumeric identifiers.
Programs
Biospecimen
Services
Collaborations
Vision & Mission
Mission: To establish a high quality reliable resource of a wide-range of biospecimen for regulated use in new technology/product development in academia and industry to facilitate tranlational research in both clicnical and basic sciences globally.
Vision: To adhere to the best practices in providing reliable, retrievable, high quality biological resources and to facilitate capacity building in biobanking at a national level by means of training, collaboration and knowledge exchange.
Infrastructure
The Biorepository is housed in a 2966 square feet facility, which has been established as per the requirements of ISO 20387:2018 standard and ISBER best practices. Six separate rooms have been created to segregate different activities namely accessioning, nucleic acid isolation, biospecimen archival, COVID-19 biospecimen processing, PBMC isolation and documentation. All equipment is calibrated and validated as per the requirements of ISO 17025: 2017 standard from an accredited third party agency.
The facility is equipped with -80°C deep freezers (n=34), -20°C freezers (n=1), 5±3°C Refrigerator (n=2), Liquid Nitrogen Storage Tanks (n=9), Cryoshippers (n=4) and other biospecimen processing equipment such as Biosafety cabinets (n=3), Centrifuges (n=3), Incubators (n=2) & Spectrophotometer (n=1).
Services
NCR Biotech Science Cluster Biorepository provides services for biospecimen collection, processing & storage (Deep freezer/Liquid nitrogen/Room temperature) as per need. Under dissemination of knowledge, the facility provides training on collection, processing of varied biospecimen. The facility has also trained interested researchers on setting up research platforms at the study sites and institutional biorepositories as per the best practices.
Biospecimen Processing Facility
Peripheral blood mononuclear cell (PBMC) Isolation from whole blood
Nucleic acid (DNA) extraction, sera and plasma preparation from whole blood
Biospecimen Archival Facility
The facility has the capacity to store 2 ml aliquots of at least 1.6 million biospecimen. It is equipped with 34 deep freezers (-80°C) and 9 liquid nitrogen containers for archival at their optimum temperatures.
Training of Manpower on processing of samples and biorepository guidelines
The facility supports national development efforts by training personnel from the industry, academia etc. in the area of biobanking governing principles and policies.
Research Programs
Summary of biospecimen archived at the Biorepository
| Clinical Cohorts* | Types of samples | No. of participants | No. of aliquots archived | No. of aliquots retrieved |
|---|---|---|---|---|
| GARBH-INI Cohort | Serum, Plasma, DNA, Urine and Blood as PAX gene tubes, Placental tissues, cord blood samples, high vaginal swabs | ~ 9382 | ~ 1150000 | ~ 32000 |
| COVID-19 Consortia | Serum, Plasma, NP/OP swabs, PBMCs | ~ 8600 | ~ 145000 | ~ 21000 |
| Paediatric Renal Biology Program | Serum, Plasma, DNA, Urine and Blood as PAX gene tubes | ~ 1020 | ~ 27000 | NIL |
| Gestational Diabetes Mellitus (GDM) Study | Serum Plasma | ~ 500 | ~ 5000 | NIL |
| Gall bladder Cancer Registry | Bile fluid, Gall bladder biopsy | ~ 30 | ~ 125 | ~ 20 |
| DRIVEN 2020 | Serum | ~ 22535 | ~ 61473 | ~ 20 |
| GIISER | Serum, Plasma, DNA, Urine and Blood as PAX gene tubes, Placental tissues, cord blood samples, high vaginal swabs | - | - | - |
| NEO-SEPSIS | Cord DNA, Rectal and Vaginal Swabs, Rectal and Vaginal Isolates | - | - | - |
*GARBH-INI = 'interdisciplinary Group for Advance Research on BirtH outcomes - DBT INdia Initiative';
*DRIVEN 2020 = DBT's Resource of Indian Vaccine Epidemiology Network 2020;
*GIISER = Global Immunology & Immune Sequencing for Epidemic Response;
Collaborations
The Biorepository has established collaborations with academia, hospitals as well as private labs under various studies.
DBT COVID-19 Consortium
National Biopharma Mission
All India Institute of Medical Sciences, New Delhi
Safdarjung Hospital (VMMCSH)
National Institute of Immunology
Makunda Christian Leprosy and General Hospital
Civil Hospital Gurugram
Christian Medical College, Vellore
Medanta Hospital, Gurugram
ESIC Medical College and Hospital, Faridabad
Lok Nayak Jai Prakash Narayan (LNJP) Hospital, New Delhi
Committees
Various committees have been constituted for the proper functioning of the Biorepository Facility
Scientific Advisory Committee
Dr. Deepali Jain, Pathologist, AIIMS (Member)
Dr. Sudip Kumar Datta, Head Lab Medicine, AIIMS (Member)
Dr. Ekta Gupta, Microbiologist, ILBS (Member)
Chairperson – The Executive Director, THSTI
Member Secretary – Dr. Pallavi Kshetrapal, Associate Professor, THSTI
Access Control Committee (COVID-19)
Dr. V.S. Chauhan, Emeritus Scientist, ICGEB
Dr. Subrata Sinha, Professor & Head Department of Biochemistry, AIIMS, Delhi
Dr. Jyoti Logani, Scientist E, Department of Biotechnology (DBT)
Dr. Shinjini Bhatnagar, Professor of Eminence, THSTI
Dr. Pallavi Kshetrapal, Associate Professor, THSTI
Dr. Savita Singh, Junior Research Scientist,THSTI
Chairperson – Dr. V.S. Chauhan
Member Secretary – Dr. Pallavi Kshetrapal
Institutional Ethics Committee (Biomedical and Health Research)
Prof. Satinder Aneja, Professor, Sharda University
Prof. Subir Kumar Maulik, Emeritus Scientist, ICMR
Dr. Arti Kapil Professor, AIIMS New Delhi
Dr. Suvasini Sharma, Associate Professor, Lady Hardinge Medical College and associated Kalawati Saran Children's Hospital
Dr. Ujjayini Ray, Professor of History, Lady Shriram College for Women
Dr. Bhabatosh Das, Associate Professor, THSTI
Dr. Shailaja Sopory, Principal Scientist-II
Mr. Munawwar Naseem, Legal - Dua Associates
Ms. Jasmine Singh, Hotel Management Professional
Ms. Vidhya Krishnamoorthy, Technical Manager (Grants Coordinator)
Chairperson - Prof. Satinder Aneja
Member Secretary - Ms. Vidhya Krishnamoorthy
Institutional Biosafety Committee
Dr. Vinay Kumar Nandicoori, Director, CSIR-CCMB
Dr. Prasenjit Guchhait, Professor, RCB
Dr. Milan Surjit, Professor
Dr. Krishnamohan Atmakuri, Associate Professor
Dr. Bhabatosh Das, Associate Professor
Dr. Nitya Wadhwa, Associate Professor
Dr. Susmita Chaudhuri, Assistant Professor
Dr. Shailaja Sopory, Principal Scientist-II
Chairperson - Dr. Krishnamohan Atmakuri
Member Secretary – Dr. Milan Surjit
EHS Committee
Dr. Nisheeth Agarwal, Professor
Dr. Krishnamohan Atmakuri, Associate Professor
Dr. Nitya Wadhwa, Associate Professor
Dr. Susmita Chaudhuri, Assistant Professor
Dr. Dinesh Mahajan, Principal Scientist-II
Mr. Vishal Gupta, Instrumentation Engineer
Mr. Narender Sharma, Senior Technical Officer (Civil)
Dr. Meenakshi Sharma, Executive Assistant
Chairperson – Dr. Nisheeth Agarwal
Co-chairperson - Dr. Susmita Chaudhuri
Member Secretary – Mr. Vishal Gupta
Team
A strong team comprising field experts contributing to the overall quality and success of the Biorepository Facility
Governance
Dr. Jayanta Bhattacharya
DEAN, Executive Director(Additional Charge)
Dr. Shinjini Bhatnagar
Distinguished Professor
Dr. Pallavi Kshetrapal
Associate Professor & Faculty In-ChargeScientific
Dr. Pallavi Kshetrapal
Associate Professor & Faculty In-Charge
Dr. Savita Singh
Jr. Research ScientistTechnical
Ajay Kumar
Technical Officer-II
Dr. Tahreem Sahar
Technical Officer-I
Amit Kumar
Laboratory Technician
Ekta
Laboratory Technician
Vinod
Technical Assistant
Naveen
Laboratory Technician
Sachin Kumar
Laboratory Technician
Ram Kumar
Laboratory Technician
Ajay
Project Assistant
Kishan Singh Gujjar
Laboratory Technician
Kamal Pindari
Laboratory Technician
Aakash
Project Technician-IIIQuality Manangement
Zafar Abbas
Quality Assurance Manager
Dr. Pratima Pandey
Quality Control ManagerData & Biorepository Information Management
Prem Pratap Singh
Data Entry Officer
Tarun Barkoti
Data Entry OperatorGallery
Biorepository Facility View through Camera-Eye
Pricing
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Free
$0 / month
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$19 / month
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Ultimate
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Frequently Asked Questioins
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Contact
How to Use THSTI Biorepository Services?
For any enquiries and queries, Contact :
Our Address
Translational Health Science and Technology Institute (THSTI)
NCR Biotech Science Cluster,
3rd Milestone, Faridabad-Gurgaon Expressway,
Faridabad - Haryana 121001, INDIA
Email Us
biorepository@thsti.res.in
savitasingh@thsti.res.in
Call Us
+91 129 2876341
+91 129 2876198